canprot: Chemical Metrics of Differentially Expressed Proteins

Chemical metrics of differentially expressed proteins in cancer and cell culture proteomics experiments. Data files in the package have amino acid compositions of proteins obtained from UniProt and >250 published lists of up- and down-regulated proteins in different cancer types and laboratory experiments. Functions are provided to calculate chemical metrics including protein length, grand average of hydropathicity (GRAVY), isoelectric point (pI), carbon oxidation state, and stoichiometric hydration state; the latter two are described in Dick et al. (2020) <doi:10.5194/bg-17-6145-2020>. The vignettes visualize differences of chemical metrics between up- and down-regulated proteins and list literature references for all datasets.

Version: 1.1.2
Depends: R (≥ 3.1.0), CHNOSZ (≥ 1.3.2)
Imports: xtable, MASS, rmarkdown
Suggests: knitr, testthat
Published: 2022-01-17
Author: Jeffrey Dick ORCID iD [aut, cre], Ben Bolker ORCID iD [ctb]
Maintainer: Jeffrey Dick <j3ffdick at>
License: GPL-2 | GPL-3 [expanded from: GPL (≥ 2)]
NeedsCompilation: no
Citation: canprot citation info
Materials: README NEWS
In views: Omics
CRAN checks: canprot results


Reference manual: canprot.pdf
Vignettes: canprot: Chemical metrics of differentially expressed proteins


Package source: canprot_1.1.2.tar.gz
Windows binaries: r-devel:, r-release:, r-oldrel:
macOS binaries: r-release (arm64): canprot_1.1.2.tgz, r-oldrel (arm64): canprot_1.1.2.tgz, r-release (x86_64): canprot_1.1.2.tgz
Old sources: canprot archive


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