SEARS: Seamless Dose Escalation/Expansion with Adaptive Randomization Scheme

A seamless design that combines phase I dose escalation based on toxicity with phase II dose expansion and dose comparison based on efficacy.

Version: 0.1.0
Depends: BOIN
Suggests: knitr, rmarkdown
Published: 2023-06-29
Author: Chia-Wei Hsu [aut, cre], Haitao Pan [aut]
Maintainer: Chia-Wei Hsu <Chia-Wei.Hsu at>
License: GPL-2
NeedsCompilation: no
CRAN checks: SEARS results


Reference manual: SEARS.pdf
Vignettes: Phase I/II seamless dose escalation/expansion with adaptive randomization scheme


Package source: SEARS_0.1.0.tar.gz
Windows binaries: r-devel:, r-release:, r-oldrel:
macOS binaries: r-release (arm64): SEARS_0.1.0.tgz, r-oldrel (arm64): SEARS_0.1.0.tgz, r-release (x86_64): SEARS_0.1.0.tgz


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